Monday, 15:45 - 16:10 h, Room: H 2033


Rasmus Bokrantz
Multi-criteria optimization for volumetric-modulated arc therapy by convex decompositions


Volumetric-modulated arc therapy (VMAT) is a technique for rotational radiation therapy that has gained widespread clinical use due to its ability of improving delivery efficiency without compromising treatment quality. Treatment planning for VMAT is a challenging multi-criteria decision problem due to a high-dimensional trade-off between tumor coverage and sparing of healthy structures in the vicinity of the target volume. Here, an approach to multi-criteria VMAT optimization is presented that relies on two convex decompositions of an initially nonconvex problem formulation. An infeasible relaxation with the elements of the energy fluence vector as variables is first used to define a global trade-off between conflicting objectives. The solution to the relaxed problem is subsequently converted into a deliverable VMAT plan. A feasible restriction with segment weights as variables is finally used to evaluate deliverable solutions in its neighborhood. The practical value of the presented method is discussed in view of comparative results with a commercially available single-objective method.


Talk 2 of the contributed session Mon.3.H 2033
"Therapy planning" [...]
Cluster 12
"Life sciences & healthcare" [...]


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