Wednesday, 16:15 - 16:40 h, Room: MA 376


Marina Epelman
A column generation-based algorithm for Volumetric Modulated Arc Therapy (VMAT) treatment plan optimization

Coauthors: Xiejun Gu, Xun Jia, Steve B. Jiang, Fei Peng, Edwin Romeijn


External beam radiation therapy is a common treatment for many types of cancer. During such treatment, radiation is delivered with a gantry, equipped with a radiation source, that is pointed at the patient from various angles. Optimization models are commonly used in individualized treatment planning, and formulation and solution methods for such models are an area of active research. VMAT is a particular technique for delivering radiation, in which the gantry continuously rotates around the patient while the leaves of a multi-leaf collimator (MLC) move in and out of the radiation field to shape it. This technique has the potential to produce treatments of high quality similar to, e.g., Intensity Modulated Radiation Therapy (IMRT), but requiring less time for delivery. Recently, comercial systems capable of delivering VMAT treatments became available, necessitating the development of relevant treatment planning methods. We propose one such method, which uses optimization models and column generation-based heuristics to produce high-quality VMAT treatment plans that allow for dynamically adjustable gantry speed and dose rate, and MLC leaf speed constraints.


Talk 3 of the invited session Wed.3.MA 376
"Radiation therapy treatment planning" [...]
Cluster 12
"Life sciences & healthcare" [...]


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