Thursday, 13:45 - 14:10 h, Room: MA 376


Nahid Jafariasbagh
Optimal individual matching to evaluate treatment in the stroke trails

Coauthors: Leonid Churilov, John Hearne


The aim of this work is to make an individual matching of patients with multiple attributes from two groups of therapy. The problem is investigating the outcomes of the two groups of patients in the stroke trails which some treated by alteplase and the others controlled by placebo.
To address the problem we modeled the problem as an integer program using assignment formulation. Our proposed models will consider the trade-off between the three objectives: maximize the number of matches, minimize the age difference, and minimize the stroke severity index difference. We applied our models for two data sets EPITHET and NINDS. To demonstrate the relationship between the sample size and the number of matches we did a simulation by generating thousands of patients and proved our assumptions.


Talk 2 of the contributed session Thu.2.MA 376
"Scheduling, assignment and matching in healthcare" [...]
Cluster 12
"Life sciences & healthcare" [...]


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